The model proved capable of simulating pharmacokinetic profiles with accuracy. Conversely, residual parameters, whose value is unknown, are regressed exploiting experimental data. The model features a system of ordinary differential equations, where most of the model parameters are either assigned or individualized for a given horse, using literature data and correlations. The proposed model is based on physiology but adopts the minimal compartmental architecture necessary to describe the experimental data. Seller assumes all responsibility for this listing.
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Researchers and medical doctors can profit from the application of mathematical models as supporting tools to optimize the pharmacological treatment of animal species. Dreamweave Girls Disney Rash Guard Set: Clothing, : Nathan Zipster Lite Running Belt. Tramadol is an opioid analgesic also used for veterinary treatments. ABSTRACT: This work proposes an application of a minimal complexity physiologically based pharmacokinetic model to predict tramadol concentration vs time profiles in horses.
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